Perfect Mismatch narrates the tale of an architect Aman (Anubhav Anand) who falls in love with Neha (Nandana). But things begin to turn for the worse as his orthodox uncle (Boman) who has brought him up meets Neha’s dad (Kher). Their first meeting itself sets the tone for the things lying ahead. Now it is up to the two lovers to find a way out to bring both the warring families together. What crazy mix up it all leads to and what pleasant changes it brings about in all the characters involved forms the rest of the plot.